USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: Q15257 USC-OGP 2-DE database:  Q15257 Q15257 General information about the entry View entry in simple text format Entry name PTPA_HUMAN Primary accession number Q15257 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Serine/threonine-protein phosphatase 2A activator; EC=5.2.1.8; AltName: Full=PP2A, subunit B', PR53 isoform; AltName: Full=Phosphotyrosyl phosphatase activator; Short=PTPA; AltName: Full=Serine/threonine-protein phosphatase 2A regulatory subunit 4; AltName: Full=Serine/threonine-protein phosphatase 2A regulatory subunit B';. Gene name Name=PPP2R4 Synonyms=PTPA Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0435: pI=5.81; Mw=39149 PLATELET_5-6 {PLATELET 5-6} Homo sapiens (Human)   map experimental info   PLATELET_5-6 MAP LOCATIONS: SPOT OGP-0720: pI=5.84; Mw=39327 SPOT OGP-0725: pI=5.79; Mw=38077 Cross-references UniProtKB/Swiss-Prot Q15257; PTPA_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name PTPA_HUMAN Primary accession number Q15257 Secondary accession number(s) A2A347 A9IZU4 B4DXM4 Q15258 Q53GZ3 Q5TZQ2 Q9BUK1 Q9NNZ7 Q9NNZ8 Q9NNZ9 Sequence was last modified on  October 17, 2006 (version 3) Annotations were last modified on  March 15, 2017 (version 155) Name and origin of the protein Description RecName: Full=Serine/threonine-protein phosphatase 2A activator; EC=5.2.1.8; AltName: Full=PP2A, subunit B', PR53 isoform; AltName: Full=Phosphotyrosyl phosphatase activator; Short=PTPA; AltName: Full=Serine/threonine-protein phosphatase 2A regulatory subunit 4; AltName: Full=Serine/threonine-protein phosphatase 2A regulatory subunit B'; Gene name Name=PPP2R4 Synonyms=PTPA Encoded on Name=PPP2R4; Synonyms=PTPA Keywords 3D-structure; Acetylation; Alternative splicing; ATP-binding; Complete proteome; Cytoplasm; Direct protein sequencing; Isomerase; Nucleotide-binding; Nucleus; Polymorphism; Reference proteome; Rotamase. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL X73478; CAA51873.1; -; mRNA EMBL X86428; CAA60163.1; -; Genomic_DNA EMBL X86429; CAA60163.1; JOINED; Genomic_DNA EMBL X86430; CAA60163.1; JOINED; Genomic_DNA EMBL X86432; CAA60163.1; JOINED; Genomic_DNA EMBL X86434; CAA60163.1; JOINED; Genomic_DNA EMBL X86435; CAA60163.1; JOINED; Genomic_DNA EMBL X86436; CAA60163.1; JOINED; Genomic_DNA EMBL X86437; CAA60163.1; JOINED; Genomic_DNA EMBL X86438; CAA60163.1; JOINED; Genomic_DNA EMBL X86439; CAA60163.1; JOINED; Genomic_DNA EMBL X86428; CAB77601.1; -; Genomic_DNA EMBL X86429; CAB77601.1; JOINED; Genomic_DNA EMBL X86430; CAB77601.1; JOINED; Genomic_DNA EMBL X86431; CAB77601.1; JOINED; Genomic_DNA EMBL X86432; CAB77601.1; JOINED; Genomic_DNA EMBL X86434; CAB77601.1; JOINED; Genomic_DNA EMBL X86435; CAB77601.1; JOINED; Genomic_DNA EMBL X86436; CAB77601.1; JOINED; Genomic_DNA EMBL X86437; CAB77601.1; JOINED; Genomic_DNA EMBL X86438; CAB77601.1; JOINED; Genomic_DNA EMBL X86439; CAB77601.1; JOINED; Genomic_DNA EMBL X86428; CAB77602.1; -; Genomic_DNA EMBL X86429; CAB77602.1; JOINED; Genomic_DNA EMBL X86432; CAB77602.1; JOINED; Genomic_DNA EMBL X86434; CAB77602.1; JOINED; Genomic_DNA EMBL X86435; CAB77602.1; JOINED; Genomic_DNA EMBL X86436; CAB77602.1; JOINED; Genomic_DNA EMBL X86437; CAB77602.1; JOINED; Genomic_DNA EMBL X86438; CAB77602.1; JOINED; Genomic_DNA EMBL X86439; CAB77602.1; JOINED; Genomic_DNA EMBL X86428; CAB77603.1; -; Genomic_DNA EMBL X86429; CAB77603.1; JOINED; Genomic_DNA EMBL X86430; CAB77603.1; JOINED; Genomic_DNA EMBL X86434; CAB77603.1; JOINED; Genomic_DNA EMBL X86435; CAB77603.1; JOINED; Genomic_DNA EMBL X86436; CAB77603.1; JOINED; Genomic_DNA EMBL X86437; CAB77603.1; JOINED; Genomic_DNA EMBL X86438; CAB77603.1; JOINED; Genomic_DNA EMBL X86439; CAB77603.1; JOINED; Genomic_DNA EMBL AK302043; BAG63436.1; -; mRNA EMBL BT020119; AAV38922.1; -; mRNA EMBL AK222788; BAD96508.1; -; mRNA EMBL AL158151; CAM14695.1; -; Genomic_DNA EMBL AL158151; CAP58847.2; -; Genomic_DNA EMBL CH471090; EAW87876.1; -; Genomic_DNA EMBL CH471090; EAW87882.1; -; Genomic_DNA EMBL BC002545; AAH02545.1; -; mRNA EMBL BC011605; AAH11605.1; -; mRNA CCDS CCDS65156.1; -. [Q15257-3]; . CCDS CCDS6920.1; -. [Q15257-2]; . PIR A54021; A54021; . RefSeq NP_001180326.1; NM_001193397.1; . RefSeq NP_001258761.1; NM_001271832.1. [Q15257-3]; . RefSeq NP_066954.2; NM_021131.4. [Q15257-2]; . RefSeq NP_821067.1; NM_178000.2. [Q15257-2]; . RefSeq NP_821068.1; NM_178001.2. [Q15257-1]; . RefSeq NP_821070.1; NM_178003.2. [Q15257-4]; . UniGene Hs.400740; -; . PDB 2G62; X-ray; 1.60 A; A=22-358 PDB 2HV6; X-ray; 1.90 A; A/B=1-358 PDB 2HV7; X-ray; 2.50 A; A/B/C/D/E/F/G/H=1-358 PDB 2IXM; X-ray; 1.50 A; A=20-357 PDB 4LAC; X-ray; 2.82 A; B=19-358 PDB 4NY3; X-ray; 1.80 A; A/B=22-358 PDBsum 2G62; -; . PDBsum 2HV6; -; . PDBsum 2HV7; -; . PDBsum 2IXM; -; . PDBsum 4LAC; -; . PDBsum 4NY3; -; . ProteinModelPortal Q15257; -; . SMR Q15257; -; . BioGrid 111516; 61; . IntAct Q15257; 18; . MINT MINT-3031079; -; . ChEMBL CHEMBL2505; -; . iPTMnet Q15257; -; . PhosphoSitePlus Q15257; -; . SwissPalm Q15257; -; . BioMuta PPP2R4; -; . DMDM 116242737; -; . OGP Q15257; -; . EPD Q15257; -; . MaxQB Q15257; -; . PeptideAtlas Q15257; -; . PRIDE Q15257; -; . DNASU 5524; -; . Ensembl ENST00000337738; ENSP00000337448; ENSG00000119383. [Q15257-1]; . Ensembl ENST00000355007; ENSP00000347109; ENSG00000119383. [Q15257-4]; . Ensembl ENST00000357197; ENSP00000349726; ENSG00000119383. [Q15257-3]; . Ensembl ENST00000358994; ENSP00000351885; ENSG00000119383. [Q15257-2]; . Ensembl ENST00000393370; ENSP00000377036; ENSG00000119383. [Q15257-2]; . GeneID 5524; -; . KEGG hsa:5524; -; . UCSC uc004bxl.3; human. [Q15257-1]; . CTD 5524; -; . DisGeNET 5524; -; . GeneCards PTPA; -; . HGNC HGNC:9308; PPP2R4; . HPA CAB022068; -; . HPA CAB035999; -; . HPA HPA005695; -; . MIM 600756; gene; . neXtProt NX_Q15257; -; . OpenTargets ENSG00000119383; -; . PharmGKB PA33671; -; . GeneTree ENSGT00390000011500; -; . HOVERGEN HBG019168; -; . InParanoid Q15257; -; . KO K17605; -; . OMA TGHEMAF; -; . OrthoDB EOG091G0ITS; -; . PhylomeDB Q15257; -; . TreeFam TF105555; -; . SIGNOR Q15257; -; . ChiTaRS PPP2R4; human; . EvolutionaryTrace Q15257; -; . GeneWiki PPP2R4; -; . GenomeRNAi 5524; -; . PRO PR:Q15257; -; . Proteomes UP000005640; Chromosome 9; . Bgee ENSG00000119383; -; . CleanEx HS_PPP2R4; -; . ExpressionAtlas Q15257; baseline and differential; . Genevisible Q15257; HS; . GO GO:0034704; C:calcium channel complex; IDA:BHF-UCL; . GO GO:0005737; C:cytoplasm; IDA:UniProtKB; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005654; C:nucleoplasm; IDA:HPA; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0000159; C:protein phosphatase type 2A complex; IDA:BHF-UCL; . GO GO:0005524; F:ATP binding; IDA:HGNC; . GO GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IBA:GO_Central; . GO GO:0046982; F:protein heterodimerization activity; TAS:HGNC; . GO GO:0042803; F:protein homodimerization activity; IDA:HGNC; . GO GO:0051721; F:protein phosphatase 2A binding; IDA:HGNC; . GO GO:0019888; F:protein phosphatase regulator activity; IDA:HGNC; . GO GO:0008160; F:protein tyrosine phosphatase activator activity; IDA:HGNC; . GO GO:0005102; F:receptor binding; IPI:BHF-UCL; . GO GO:0030472; P:mitotic spindle organization in nucleus; IBA:GO_Central; . GO GO:0032515; P:negative regulation of phosphoprotein phosphatase activity; IDA:HGNC; . GO GO:0035308; P:negative regulation of protein dephosphorylation; IDA:HGNC; . GO GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB; . GO GO:0032516; P:positive regulation of phosphoprotein phosphatase activity; IDA:HGNC; . GO GO:0035307; P:positive regulation of protein dephosphorylation; IDA:HGNC; . GO GO:0043666; P:regulation of phosphoprotein phosphatase activity; IDA:HGNC; . CDD cd04087; PTPA; 1; . InterPro IPR004327; Phstyr_phstse_ac; . PANTHER PTHR10012; PTHR10012; 1; . Pfam PF03095; PTPA; 1; . PIRSF PIRSF016325; Phstyr_phstse_ac; 1; .

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